The neuroprotective effect of latanoprost acts via klotho‐mediated suppression of calpain activation after optic nerve transection

Latanoprost was first developed for use in glaucoma therapy as an ocular hypotensive agent targeting the prostaglandin F2α (FP) receptor. Subsequently, latanoprost showed a neuroprotective effect, an additional pharmacological action. However, although it is well‐known that latanoprost exerts an ocu...

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Detalles Bibliográficos
Autores principales: Yamamoto, Kotaro, Sato, Kota, Yukita, Masayoshi, Yasuda, Masayuki, Omodaka, Kazuko, Ryu, Morin, Fujita, Kosuke, Nishiguchi, Koji M., Machida, Shigeki, Nakazawa, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299490/
https://www.ncbi.nlm.nih.gov/pubmed/27859240
http://dx.doi.org/10.1111/jnc.13902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299490/
https://www.ncbi.nlm.nih.gov/pubmed/27859240
http://dx.doi.org/10.1111/jnc.13902

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