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Native‐like Env trimers as a platform for HIV‐1 vaccine design

We describe the development and potential use of various designs of recombinant HIV‐1 envelope glycoprotein trimers that mimic the structure of the virion‐associated spike, which is the target for neutralizing antibodies. The goal of trimer development programs is to induce broadly neutralizing anti...

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Detalles Bibliográficos
Autores principales: Sanders, Rogier W., Moore, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299501/
https://www.ncbi.nlm.nih.gov/pubmed/28133806
http://dx.doi.org/10.1111/imr.12481