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Native‐like Env trimers as a platform for HIV‐1 vaccine design
We describe the development and potential use of various designs of recombinant HIV‐1 envelope glycoprotein trimers that mimic the structure of the virion‐associated spike, which is the target for neutralizing antibodies. The goal of trimer development programs is to induce broadly neutralizing anti...
Autores principales: | Sanders, Rogier W., Moore, John P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299501/ https://www.ncbi.nlm.nih.gov/pubmed/28133806 http://dx.doi.org/10.1111/imr.12481 |
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