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Small‐Molecule‐Induced and Cooperative Enzyme Assembly on a 14‐3‐3 Scaffold

Scaffold proteins regulate cell signalling by promoting the proximity of putative interaction partners. Although they are frequently applied in cellular settings, fundamental understanding of them in terms of, amongst other factors, quantitative parameters has been lagging behind. Here we present a...

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Detalles Bibliográficos
Autores principales: den Hamer, Anniek, Lemmens, Lenne J. M., Nijenhuis, Minke A. D., Ottmann, Christian, Merkx, Maarten, de Greef, Tom F. A., Brunsveld, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299510/
https://www.ncbi.nlm.nih.gov/pubmed/27897387
http://dx.doi.org/10.1002/cbic.201600631