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Nanoscale diffusion in the synaptic cleft and beyond measured with time-resolved fluorescence anisotropy imaging

Neural activity relies on molecular diffusion within nanoscopic spaces outside and inside nerve cells, such as synaptic clefts or dendritic spines. Measuring diffusion on this small scale in situ has not hitherto been possible, yet this knowledge is critical for understanding the dynamics of molecul...

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Detalles Bibliográficos
Autores principales: Zheng, Kaiyu, Jensen, Thomas P., Savtchenko, Leonid P., Levitt, James A., Suhling, Klaus, Rusakov, Dmitri A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299514/
https://www.ncbi.nlm.nih.gov/pubmed/28181535
http://dx.doi.org/10.1038/srep42022