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Motuporamine Derivatives as Antimicrobial Agents and Antibiotic Enhancers against Resistant Gram‐Negative Bacteria

Dihydromotuporamine C and its derivatives were evaluated for their in vitro antimicrobial activities and antibiotic enhancement properties against Gram‐negative bacteria and clinical isolates. The mechanism of action of one of these derivatives, MOTU‐N44, was investigated against Enterobacter aeroge...

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Detalles Bibliográficos
Autores principales: Borselli, Diane, Blanchet, Marine, Bolla, Jean‐Michel, Muth, Aaron, Skruber, Kristen, Phanstiel, Otto, Brunel, Jean Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299527/
https://www.ncbi.nlm.nih.gov/pubmed/28098416
http://dx.doi.org/10.1002/cbic.201600532