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One‐stage individual participant data meta‐analysis models: estimation of treatment‐covariate interactions must avoid ecological bias by separating out within‐trial and across‐trial information
Stratified medicine utilizes individual‐level covariates that are associated with a differential treatment effect, also known as treatment‐covariate interactions. When multiple trials are available, meta‐analysis is used to help detect true treatment‐covariate interactions by combining their data. M...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299543/ https://www.ncbi.nlm.nih.gov/pubmed/27910122 http://dx.doi.org/10.1002/sim.7171 |