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Effect of the Southeast Asian Ovalocytosis Deletion on the Conformational Dynamics of Signal-Anchor Transmembrane Segment 1 of Red Cell Anion Exchanger 1 (AE1, Band 3, or SLC4A1)

[Image: see text] The first transmembrane (TM1) helix in the red cell anion exchanger (AE1, Band 3, or SLC4A1) acts as an internal signal anchor that binds the signal recognition particle and directs the nascent polypeptide chain to the endoplasmic reticulum (ER) membrane where it moves from the tra...

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Detalles Bibliográficos
Autores principales: Fowler, Philip W., Sansom, Mark S. P., Reithmeier, Reinhart A. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299548/
https://www.ncbi.nlm.nih.gov/pubmed/28068080
http://dx.doi.org/10.1021/acs.biochem.6b00966