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Creatine Enhances Mitochondrial-Mediated Oligodendrocyte Survival After Demyelinating Injury

Chronic oligodendrocyte loss, which occurs in the demyelinating disorder multiple sclerosis (MS), contributes to axonal dysfunction and neurodegeneration. Current therapies are able to reduce MS severity, but do not prevent transition into the progressive phase of the disease, which is characterized...

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Detalles Bibliográficos
Autores principales: Chamberlain, Kelly A., Chapey, Kristen S., Nanescu, Sonia E., Huang, Jeffrey K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299567/
https://www.ncbi.nlm.nih.gov/pubmed/28069926
http://dx.doi.org/10.1523/JNEUROSCI.1941-16.2016