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Creatine Enhances Mitochondrial-Mediated Oligodendrocyte Survival After Demyelinating Injury
Chronic oligodendrocyte loss, which occurs in the demyelinating disorder multiple sclerosis (MS), contributes to axonal dysfunction and neurodegeneration. Current therapies are able to reduce MS severity, but do not prevent transition into the progressive phase of the disease, which is characterized...
Autores principales: | Chamberlain, Kelly A., Chapey, Kristen S., Nanescu, Sonia E., Huang, Jeffrey K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299567/ https://www.ncbi.nlm.nih.gov/pubmed/28069926 http://dx.doi.org/10.1523/JNEUROSCI.1941-16.2016 |
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