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Differences in the transcriptome of medullary thyroid cancer regarding the status and type of RET gene mutations

Medullary thyroid cancer (MTC) can be caused by germline mutations of the RET proto-oncogene or occurs as a sporadic form. It is well known that RET mutations affecting the cysteine-rich region of the protein (MEN2A-like mutations) are correlated with different phenotypes than those in the kinase do...

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Detalles Bibliográficos
Autores principales: Oczko-Wojciechowska, Malgorzata, Swierniak, Michal, Krajewska, Jolanta, Kowalska, Malgorzata, Kowal, Monika, Stokowy, Tomasz, Wojtas, Bartosz, Rusinek, Dagmara, Pawlaczek, Agnieszka, Czarniecka, Agnieszka, Szpak-Ulczok, Sylwia, Gawlik, Tomasz, Chmielik, Ewa, Tyszkiewicz, Tomasz, Nikiel, Barbara, Lange, Dariusz, Jarzab, Michal, Wiench, Malgorzata, Jarzab, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299608/
https://www.ncbi.nlm.nih.gov/pubmed/28181547
http://dx.doi.org/10.1038/srep42074