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Dissecting the brown adipogenic regulatory network using integrative genomics

Brown adipocytes regulate energy expenditure via mitochondrial uncoupling, which makes them attractive therapeutic targets to tackle obesity. However, the regulatory mechanisms underlying brown adipogenesis are still poorly understood. To address this, we profiled the transcriptome and chromatin sta...

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Detalles Bibliográficos
Autores principales: Pradhan, Rachana N., Bues, Johannes J., Gardeux, Vincent, Schwalie, Petra C., Alpern, Daniel, Chen, Wanze, Russeil, Julie, Raghav, Sunil K., Deplancke, Bart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299609/
https://www.ncbi.nlm.nih.gov/pubmed/28181539
http://dx.doi.org/10.1038/srep42130