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Gfi1(Cre) mice have early onset progressive hearing loss and induce recombination in numerous inner ear non-hair cells

Studies of developmental and functional biology largely rely on conditional expression of genes in a cell type-specific manner. Therefore, the importance of specificity and lack of inherent phenotypes for Cre-driver animals cannot be overemphasized. The Gfi1(Cre) mouse is commonly used for condition...

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Detalles Bibliográficos
Autores principales: Matern, Maggie, Vijayakumar, Sarath, Margulies, Zachary, Milon, Beatrice, Song, Yang, Elkon, Ran, Zhang, Xiaoyu, Jones, Sherri M., Hertzano, Ronna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299610/
https://www.ncbi.nlm.nih.gov/pubmed/28181545
http://dx.doi.org/10.1038/srep42079