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Gfi1(Cre) mice have early onset progressive hearing loss and induce recombination in numerous inner ear non-hair cells
Studies of developmental and functional biology largely rely on conditional expression of genes in a cell type-specific manner. Therefore, the importance of specificity and lack of inherent phenotypes for Cre-driver animals cannot be overemphasized. The Gfi1(Cre) mouse is commonly used for condition...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299610/ https://www.ncbi.nlm.nih.gov/pubmed/28181545 http://dx.doi.org/10.1038/srep42079 |