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Identification of the ADPR binding pocket in the NUDT9 homology domain of TRPM2

Activation of the transient receptor potential melastatin 2 (TRPM2) channel occurs during the response to oxidative stress under physiological conditions as well as in pathological processes such as ischemia and diabetes. Accumulating evidence indicates that adenosine diphosphate ribose (ADPR) is th...

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Detalles Bibliográficos
Autores principales: Yu, Peilin, Xue, Xiwen, Zhang, Jianmin, Hu, Xupang, Wu, Yan, Jiang, Lin-Hua, Jin, Hongwei, Luo, Jianhong, Zhang, Liangren, Liu, Zhenming, Yang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299621/
https://www.ncbi.nlm.nih.gov/pubmed/28108595
http://dx.doi.org/10.1085/jgp.201611675