Cargando…

MLL-Rearranged Leukemias—An Update on Science and Clinical Approaches

The mixed-lineage leukemia 1 (MLL1) gene (now renamed Lysine [K]-specific MethylTransferase 2A or KMT2A) on chromosome 11q23 is disrupted in a unique group of acute leukemias. More than 80 different partner genes in these fusions have been described, although the majority of leukemias result from ML...

Descripción completa

Detalles Bibliográficos
Autores principales: Winters, Amanda C., Bernt, Kathrin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299633/
https://www.ncbi.nlm.nih.gov/pubmed/28232907
http://dx.doi.org/10.3389/fped.2017.00004