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MLL-Rearranged Leukemias—An Update on Science and Clinical Approaches
The mixed-lineage leukemia 1 (MLL1) gene (now renamed Lysine [K]-specific MethylTransferase 2A or KMT2A) on chromosome 11q23 is disrupted in a unique group of acute leukemias. More than 80 different partner genes in these fusions have been described, although the majority of leukemias result from ML...
Autores principales: | Winters, Amanda C., Bernt, Kathrin M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299633/ https://www.ncbi.nlm.nih.gov/pubmed/28232907 http://dx.doi.org/10.3389/fped.2017.00004 |
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