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MLL-Rearranged Leukemias—An Update on Science and Clinical Approaches

The mixed-lineage leukemia 1 (MLL1) gene (now renamed Lysine [K]-specific MethylTransferase 2A or KMT2A) on chromosome 11q23 is disrupted in a unique group of acute leukemias. More than 80 different partner genes in these fusions have been described, although the majority of leukemias result from ML...

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Detalles Bibliográficos
Autores principales: Winters, Amanda C., Bernt, Kathrin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299633/
https://www.ncbi.nlm.nih.gov/pubmed/28232907
http://dx.doi.org/10.3389/fped.2017.00004

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