HDL-associated ApoM is anti-apoptotic by delivering sphingosine 1-phosphate to S1P1 & S1P3 receptors on vascular endothelium

BACKGROUND: High-density Lipoprotein (HDL) attenuates endothelial cell apoptosis induced by different cell-death stimuli such as oxidation or growth factor deprivation. HDL is the main plasma carrier of the bioactive lipid sphingosine 1-phosphate (S1P), which it is a signaling molecule that promotes...

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Detalles Bibliográficos
Autores principales: Ruiz, Mario, Okada, Hiromi, Dahlbäck, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299634/
https://www.ncbi.nlm.nih.gov/pubmed/28179022
http://dx.doi.org/10.1186/s12944-017-0429-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299634/
https://www.ncbi.nlm.nih.gov/pubmed/28179022
http://dx.doi.org/10.1186/s12944-017-0429-2

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