Cargando…

The lncRNA HOTAIRM1 regulates the degradation of PML-RARA oncoprotein and myeloid cell differentiation by enhancing the autophagy pathway

Increasing evidence has indicated that long noncoding RNAs (lncRNAs) are of great importance in different cell contexts. However, only a very small number of lncRNAs have been experimentally validated and functionally annotated during human hematopoiesis. Here, we report an lncRNA, HOTAIRM1, which i...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Zhen-Hua, Wang, Wen-Tao, Huang, Wei, Fang, Ke, Sun, Yu-Meng, Liu, Shu-Rong, Luo, Xue-Qun, Chen, Yue-Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299705/
https://www.ncbi.nlm.nih.gov/pubmed/27740626
http://dx.doi.org/10.1038/cdd.2016.111