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Doxycycline attenuates breast cancer related inflammation by decreasing plasma lysophosphatidate concentrations and inhibiting NF-κB activation
BACKGROUND: We previously discovered that tetracyclines increase the expression of lipid phosphate phosphatases at the surface of cells. These enzymes degrade circulating lysophosphatidate and therefore doxycycline increases the turnover of plasma lysophosphatidate and decreases its concentration. E...
Autores principales: | Tang, Xiaoyun, Wang, Xianyan, Zhao, Yuan Y., Curtis, Jonathan M., Brindley, David N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299726/ https://www.ncbi.nlm.nih.gov/pubmed/28178994 http://dx.doi.org/10.1186/s12943-017-0607-x |
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