The antimicrobial molecule trappin-2/elafin has anti-parasitic properties and is protective in vivo in a murine model of cerebral malaria

According to the WHO, and despite reduction in mortality rates, there were an estimated 438 000 malaria deaths in 2015. Therefore new antimalarials capable of limiting organ damage are still required. We show that systemic and lung adenovirus (Ad)-mediated over-expression of trappin-2 (T-2) an antib...

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Detalles Bibliográficos
Autores principales: Roussilhon, Christian, Bang, Gilles, Bastaert, Fabien, Solhonne, Brigitte, Garcia-Verdugo, Ignacio, Peronet, Roger, Druilhe, Pierre, Sakuntabhai, Anavaj, Mecheri, Salaheddine, Sallenave, Jean-Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299836/
https://www.ncbi.nlm.nih.gov/pubmed/28181563
http://dx.doi.org/10.1038/srep42243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299836/
https://www.ncbi.nlm.nih.gov/pubmed/28181563
http://dx.doi.org/10.1038/srep42243

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