Multiplexed transcriptome analysis to detect ALK, ROS1 and RET rearrangements in lung cancer

ALK, ROS1 and RET gene fusions are important predictive biomarkers for tyrosine kinase inhibitors in lung cancer. Currently, the gold standard method for gene fusion detection is Fluorescence In Situ Hybridization (FISH) and while highly sensitive and specific, it is also labour intensive, subjectiv...

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Detalles Bibliográficos
Autores principales: Rogers, Toni-Maree, Arnau, Gisela Mir, Ryland, Georgina L., Huang, Stephen, Lira, Maruja E., Emmanuel, Yvette, Perez, Omar D., Irwin, Darryl, Fellowes, Andrew P., Wong, Stephen Q., Fox, Stephen B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299839/
https://www.ncbi.nlm.nih.gov/pubmed/28181564
http://dx.doi.org/10.1038/srep42259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299839/
https://www.ncbi.nlm.nih.gov/pubmed/28181564
http://dx.doi.org/10.1038/srep42259

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