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The mitotic checkpoint regulator RAE1 induces aggressive breast cancer cell phenotypes by mediating epithelial-mesenchymal transition

The gene RAE1 encodes ribonucleic acid export 1 (RAE1), which is involved in mRNA export and is known to serve as a mitotic checkpoint regulator. In addition, RAE1 haplo-insufficiency leads to chromosome missegregation and early aging-associated phenotypes. In humans, a positive correlation has been...

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Detalles Bibliográficos
Autores principales: Oh, Ji Hoon, Hur, Ho, Lee, Ji-Yeon, Kim, Yeejeong, Seo, Younsoo, Kim, Myoung Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299842/
https://www.ncbi.nlm.nih.gov/pubmed/28181567
http://dx.doi.org/10.1038/srep42256