Microsomal Metabolism of Prochiral Polychlorinated Biphenyls Results in the Enantioselective Formation of Chiral Metabolites

[Image: see text] Polychlorinated biphenyl (PCB) congeners with multiple ortho chlorine substituents and their metabolites exist as stable rotational isomers, or atropisomers, that are nonsuperimposable mirror images of each other. Additionally, the oxidation of certain axially prochiral PCBs, such...

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Detalles Bibliográficos
Autores principales: Uwimana, Eric, Maiers, Anna, Li, Xueshu, Lehmler, Hans-Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300040/
https://www.ncbi.nlm.nih.gov/pubmed/28038482
http://dx.doi.org/10.1021/acs.est.6b05387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300040/
https://www.ncbi.nlm.nih.gov/pubmed/28038482
http://dx.doi.org/10.1021/acs.est.6b05387

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