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Microsomal Metabolism of Prochiral Polychlorinated Biphenyls Results in the Enantioselective Formation of Chiral Metabolites
[Image: see text] Polychlorinated biphenyl (PCB) congeners with multiple ortho chlorine substituents and their metabolites exist as stable rotational isomers, or atropisomers, that are nonsuperimposable mirror images of each other. Additionally, the oxidation of certain axially prochiral PCBs, such...
Autores principales: | Uwimana, Eric, Maiers, Anna, Li, Xueshu, Lehmler, Hans-Joachim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2016
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300040/ https://www.ncbi.nlm.nih.gov/pubmed/28038482 http://dx.doi.org/10.1021/acs.est.6b05387 |
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