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Ontogeny‐based immunogens for the induction of V2‐directed HIV broadly neutralizing antibodies

The development of a preventative HIV vaccine able to elicit broadly neutralizing antibodies (bNAbs) remains a major challenge. Antibodies that recognize the V2 region at the apex of the HIV envelope trimer are among the most common bNAb specificities during chronic infection and many exhibit remark...

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Detalles Bibliográficos
Autores principales: Moore, Penny L., Gorman, Jason, Doria‐Rose, Nicole A., Morris, Lynn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300058/
https://www.ncbi.nlm.nih.gov/pubmed/28133797
http://dx.doi.org/10.1111/imr.12501