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Error baseline rates of five sample preparation methods used to characterize RNA virus populations

Individual RNA viruses typically occur as populations of genomes that differ slightly from each other due to mutations introduced by the error-prone viral polymerase. Understanding the variability of RNA virus genome populations is critical for understanding virus evolution because individual mutant...

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Detalles Bibliográficos
Autores principales: Kugelman, Jeffrey R., Wiley, Michael R., Nagle, Elyse R., Reyes, Daniel, Pfeffer, Brad P., Kuhn, Jens H., Sanchez-Lockhart, Mariano, Palacios, Gustavo F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300104/
https://www.ncbi.nlm.nih.gov/pubmed/28182717
http://dx.doi.org/10.1371/journal.pone.0171333