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Error baseline rates of five sample preparation methods used to characterize RNA virus populations
Individual RNA viruses typically occur as populations of genomes that differ slightly from each other due to mutations introduced by the error-prone viral polymerase. Understanding the variability of RNA virus genome populations is critical for understanding virus evolution because individual mutant...
Autores principales: | Kugelman, Jeffrey R., Wiley, Michael R., Nagle, Elyse R., Reyes, Daniel, Pfeffer, Brad P., Kuhn, Jens H., Sanchez-Lockhart, Mariano, Palacios, Gustavo F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300104/ https://www.ncbi.nlm.nih.gov/pubmed/28182717 http://dx.doi.org/10.1371/journal.pone.0171333 |
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