Cargando…
Deciphering the molecular mechanism responsible for GCaMP6m's Ca(2+)-dependent change in fluorescence
The goal of this work is to determine how GCaMP6m’s fluorescence is altered in response to Ca(2+)-binding. Our detailed spectroscopic study reveals the simplest explanation for how GCaMP6m changes fluorescence in response to Ca(2+) is with a four-state model, in which a Ca(2+)-dependent change of th...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300113/ https://www.ncbi.nlm.nih.gov/pubmed/28182677 http://dx.doi.org/10.1371/journal.pone.0170934 |