Estimating the Respective Contributions of Human and Viral Genetic Variation to HIV Control

We evaluated the fraction of variation in HIV-1 set point viral load attributable to viral or human genetic factors by using joint host/pathogen genetic data from 541 HIV infected individuals. We show that viral genetic diversity explains 29% of the variation in viral load while host factors explain...

Descripción completa

Detalles Bibliográficos
Autores principales: Bartha, István, McLaren, Paul J., Brumme, Chanson, Harrigan, Richard, Telenti, Amalio, Fellay, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300119/
https://www.ncbi.nlm.nih.gov/pubmed/28182649
http://dx.doi.org/10.1371/journal.pcbi.1005339

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300119/
https://www.ncbi.nlm.nih.gov/pubmed/28182649
http://dx.doi.org/10.1371/journal.pcbi.1005339

Ejemplares similares