Representing high throughput expression profiles via perturbation barcodes reveals compound targets

High throughput mRNA expression profiling can be used to characterize the response of cell culture models to perturbations such as pharmacologic modulators and genetic perturbations. As profiling campaigns expand in scope, it is important to homogenize, summarize, and analyze the resulting data in a...

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Detalles Bibliográficos
Autores principales: Filzen, Tracey M., Kutchukian, Peter S., Hermes, Jeffrey D., Li, Jing, Tudor, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300121/
https://www.ncbi.nlm.nih.gov/pubmed/28182661
http://dx.doi.org/10.1371/journal.pcbi.1005335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300121/
https://www.ncbi.nlm.nih.gov/pubmed/28182661
http://dx.doi.org/10.1371/journal.pcbi.1005335

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