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Identification of several high-risk HPV inhibitors and drug targets with a novel high-throughput screening assay

Human papillomaviruses (HPVs) are oncogenic viruses that cause numerous different cancers as well as benign lesions in the epithelia. To date, there is no effective cure for an ongoing HPV infection. Here, we describe the generation process of a platform for the development of anti-HPV drugs. This s...

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Detalles Bibliográficos
Autores principales: Toots, Mart, Ustav, Mart, Männik, Andres, Mumm, Karl, Tämm, Kaido, Tamm, Tarmo, Ustav, Ene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300127/
https://www.ncbi.nlm.nih.gov/pubmed/28182794
http://dx.doi.org/10.1371/journal.ppat.1006168