Biochemical and biophysical investigations of the interaction between human glucokinase and pro-apoptotic BAD

The glycolytic enzyme glucokinase (GCK) and the pro-apoptotic protein BAD reportedly reside within a five-membered complex that localizes to the mitochondria of mammalian hepatocytes and pancreatic β-cells. Photochemical crosslinking studies using a synthetic analog of BAD’s BH3 domain and in vitro...

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Detalles Bibliográficos
Autores principales: Rexford, Alix, Zorio, Diego A. R., Miller, Brian G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300155/
https://www.ncbi.nlm.nih.gov/pubmed/28182770
http://dx.doi.org/10.1371/journal.pone.0171587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300155/
https://www.ncbi.nlm.nih.gov/pubmed/28182770
http://dx.doi.org/10.1371/journal.pone.0171587

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