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Distinct effects of endosomal escape and inhibition of endosomal trafficking on gene delivery via electrotransfection

A recent theory suggests that endocytosis is involved in uptake and intracellular transport of electrotransfected plasmid DNA (pDNA). The goal of the current study was to understand if approaches used previously to improve endocytosis of gene delivery vectors could be applied to enhancing electrotra...

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Detalles Bibliográficos
Autores principales: Cervia, Lisa D., Chang, Chun-Chi, Wang, Liangli, Yuan, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300164/
https://www.ncbi.nlm.nih.gov/pubmed/28182739
http://dx.doi.org/10.1371/journal.pone.0171699