O-prenylated 3-carboxycoumarins as a novel class of 15-LOX-1 inhibitors

Allyloxy, Isopentenyloxy, geranyloxy and farnesyloxy derivatives of 3-carboxycoumarin, at position 5, 6, 7, and 8, were synthesized and their inhibitory potency against human 15-lipoxygenase-1 (human 15-LOX-1) were determined. Among the synthetic coumarins, O-allyl and O-isopentenyl derivatives demo...

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Detalles Bibliográficos
Autores principales: Jabbari, Atena, Mousavian, Mina, Seyedi, Seyed Mohamad, Bakavoli, Mehdi, Sadeghian, Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300203/
https://www.ncbi.nlm.nih.gov/pubmed/28182779
http://dx.doi.org/10.1371/journal.pone.0171789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300203/
https://www.ncbi.nlm.nih.gov/pubmed/28182779
http://dx.doi.org/10.1371/journal.pone.0171789

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