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Rikkunshito prevents paclitaxel-induced peripheral neuropathy through the suppression of the nuclear factor kappa B (NFκB) phosphorylation in spinal cord of mice

Peripheral neuropathy is the major side effect caused by paclitaxel, a microtubule-binding antineoplastic drug. Paclitaxel-induced peripheral neuropathy causes a long-term negative impact on the patient's quality of life. However, the mechanism underlying paclitaxel-induced peripheral neuropath...

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Detalles Bibliográficos
Autores principales: Kamei, Junzo, Hayashi, Shunsuke, Sakai, Akane, Nakanishi, Yuki, Kai, Misa, Ikegami, Megumi, Ikeda, Hiroko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300261/
https://www.ncbi.nlm.nih.gov/pubmed/28182729
http://dx.doi.org/10.1371/journal.pone.0171819