Established patterns of animal study design undermine translation of disease-modifying therapies for Parkinson’s disease

Translation of disease-modifying therapies in neurodegenerative disease has been disappointing. Parkinson’s disease (PD) was used to compare patterns of preclinical study design for symptomatic and potentially disease-modifying interventions. We examined the relationship of model, intervention type...

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Detalles Bibliográficos
Autores principales: Zeiss, Caroline J., Allore, Heather G., Beck, Amanda P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300282/
https://www.ncbi.nlm.nih.gov/pubmed/28182759
http://dx.doi.org/10.1371/journal.pone.0171790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300282/
https://www.ncbi.nlm.nih.gov/pubmed/28182759
http://dx.doi.org/10.1371/journal.pone.0171790

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