Cargando…
Established patterns of animal study design undermine translation of disease-modifying therapies for Parkinson’s disease
Translation of disease-modifying therapies in neurodegenerative disease has been disappointing. Parkinson’s disease (PD) was used to compare patterns of preclinical study design for symptomatic and potentially disease-modifying interventions. We examined the relationship of model, intervention type...
Autores principales: | Zeiss, Caroline J., Allore, Heather G., Beck, Amanda P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300282/ https://www.ncbi.nlm.nih.gov/pubmed/28182759 http://dx.doi.org/10.1371/journal.pone.0171790 |
Ejemplares similares
-
Modeling pandemic to endemic patterns of SARS-CoV-2 transmission using parameters estimated from animal model data
por: Mullin, Sarah, et al.
Publicado: (2022) -
Menagerie: A text-mining tool to support animal-human translation in neurodegeneration research
por: Zeiss, Caroline J., et al.
Publicado: (2019) -
Chemical Entity Normalization for Successful Translational Development of Alzheimer’s Disease and Dementia Therapeutics
por: Mullin, Sarah, et al.
Publicado: (2023) -
Modeling SARS-CoV-2 propagation using rat coronavirus-associated shedding and transmission
por: Zeiss, Caroline J., et al.
Publicado: (2021) -
Undermining the Tower of Babel
Publicado: (1970)