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Targeting of the Fun30 nucleosome remodeller by the Dpb11 scaffold facilitates cell cycle-regulated DNA end resection

DNA double strand breaks (DSBs) can be repaired by either recombination-based or direct ligation-based mechanisms. Pathway choice is made at the level of DNA end resection, a nucleolytic processing step, which primes DSBs for repair by recombination. Resection is thus under cell cycle control, but a...

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Detalles Bibliográficos
Autores principales: Bantele, Susanne CS, Ferreira, Pedro, Gritenaite, Dalia, Boos, Dominik, Pfander, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300703/
https://www.ncbi.nlm.nih.gov/pubmed/28063255
http://dx.doi.org/10.7554/eLife.21687