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Targeting of the Fun30 nucleosome remodeller by the Dpb11 scaffold facilitates cell cycle-regulated DNA end resection
DNA double strand breaks (DSBs) can be repaired by either recombination-based or direct ligation-based mechanisms. Pathway choice is made at the level of DNA end resection, a nucleolytic processing step, which primes DSBs for repair by recombination. Resection is thus under cell cycle control, but a...
Autores principales: | Bantele, Susanne CS, Ferreira, Pedro, Gritenaite, Dalia, Boos, Dominik, Pfander, Boris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300703/ https://www.ncbi.nlm.nih.gov/pubmed/28063255 http://dx.doi.org/10.7554/eLife.21687 |
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