Isoform-specific subcellular localization and function of protein kinase A identified by mosaic imaging of mouse brain

Protein kinase A (PKA) plays critical roles in neuronal function that are mediated by different regulatory (R) subunits. Deficiency in either the RIβ or the RIIβ subunit results in distinct neuronal phenotypes. Although RIβ contributes to synaptic plasticity, it is the least studied isoform. Using i...

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Detalles Bibliográficos
Autores principales: Ilouz, Ronit, Lev-Ram, Varda, Bushong, Eric A, Stiles, Travis L, Friedmann-Morvinski, Dinorah, Douglas, Christopher, Goldberg, Jeffrey L, Ellisman, Mark H, Taylor, Susan S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300705/
https://www.ncbi.nlm.nih.gov/pubmed/28079521
http://dx.doi.org/10.7554/eLife.17681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300705/
https://www.ncbi.nlm.nih.gov/pubmed/28079521
http://dx.doi.org/10.7554/eLife.17681

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