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The ER-Mitochondria Tethering Complex VAPB-PTPIP51 Regulates Autophagy

Mitochondria form close physical associations with the endoplasmic reticulum (ER) that regulate a number of physiological functions. One mechanism by which regions of ER are recruited to mitochondria involves binding of the ER protein VAPB to the mitochondrial protein PTPIP51, which act as scaffolds...

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Detalles Bibliográficos
Autores principales: Gomez-Suaga, Patricia, Paillusson, Sebastien, Stoica, Radu, Noble, Wendy, Hanger, Diane P., Miller, Christopher C.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300905/
https://www.ncbi.nlm.nih.gov/pubmed/28132811
http://dx.doi.org/10.1016/j.cub.2016.12.038