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Expression of Viral Antigen by the Liver Leads to Chronic Infection Through the Generation of Regulatory T Cells

BACKGROUND & AIMS: The constant exposure of the liver to food and bacterial antigens through the mesenteric circulation requires it to maintain tolerance while preserving the ability to mount an effective immune response against pathogens. We investigated the contribution of the liver’s toleroge...

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Detalles Bibliográficos
Autores principales: Lapierre, Pascal, Janelle, Valérie, Langlois, Marie-Pierre, Tarrab, Esther, Charpentier, Tania, Lamarre, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301191/
https://www.ncbi.nlm.nih.gov/pubmed/28210682
http://dx.doi.org/10.1016/j.jcmgh.2015.02.002