Cargando…

Reduced Necrosis and Content of Apoptotic M1 Macrophages in Advanced Atherosclerotic Plaques of Mice With Macrophage-Specific Loss of Trpc3

In previous work we reported that ApoeKO mice transplanted with bone marrow cells deficient in the Transient Receptor Potential Canonical 3 (TRPC3) channel have reduced necrosis and number of apoptotic macrophages in advanced atherosclerotic plaques. Also, in vitro studies with polarized macrophages...

Descripción completa

Detalles Bibliográficos
Autores principales: Solanki, Sumeet, Dube, Prabhatchandra R., Birnbaumer, Lutz, Vazquez, Guillermo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301208/
https://www.ncbi.nlm.nih.gov/pubmed/28186192
http://dx.doi.org/10.1038/srep42526