CENP-A chromatin disassembly in stressed and senescent murine cells

Centromeres are chromosomal domains essential for genomic stability. We report here the remarkable transcriptional and epigenetic perturbations at murine centromeres in genotoxic stress conditions. A strong and selective transcriptional activation of centromeric repeats is detected within hours. Thi...

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Detalles Bibliográficos
Autores principales: Hédouin, Sabrine, Grillo, Giacomo, Ivkovic, Ivana, Velasco, Guillaume, Francastel, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301216/
https://www.ncbi.nlm.nih.gov/pubmed/28186195
http://dx.doi.org/10.1038/srep42520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301216/
https://www.ncbi.nlm.nih.gov/pubmed/28186195
http://dx.doi.org/10.1038/srep42520

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