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CENP-A chromatin disassembly in stressed and senescent murine cells
Centromeres are chromosomal domains essential for genomic stability. We report here the remarkable transcriptional and epigenetic perturbations at murine centromeres in genotoxic stress conditions. A strong and selective transcriptional activation of centromeric repeats is detected within hours. Thi...
Autores principales: | Hédouin, Sabrine, Grillo, Giacomo, Ivkovic, Ivana, Velasco, Guillaume, Francastel, Claire |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301216/ https://www.ncbi.nlm.nih.gov/pubmed/28186195 http://dx.doi.org/10.1038/srep42520 |
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