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FOXO1-suppressed miR-424 regulates the proliferation and osteogenic differentiation of MSCs by targeting FGF2 under oxidative stress

Recently, microRNAs (miRNAs) have been identified as key regulators of the proliferation and differentiation of mesenchymal stem cells (MSCs). Our previous in vivo study and other in vitro studies using miRNA microarrays suggest that miR-424 is involved in the regulation of bone formation. However,...

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Detalles Bibliográficos
Autores principales: Li, Liangping, Qi, Qihua, Luo, Jiaquan, Huang, Sheng, Ling, Zemin, Gao, Manman, Zhou, Zhiyu, Stiehler, Maik, Zou, Xuenong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301230/
https://www.ncbi.nlm.nih.gov/pubmed/28186136
http://dx.doi.org/10.1038/srep42331