Three-dimensional collagen matrix induces a mechanosensitive invasive epithelial phenotype

A critical step in breast cancer progression is local tissue invasion, during which cells pass from the epithelial compartment to the stromal compartment. We recently showed that malignant leader cells can promote the invasion of otherwise non-invasive epithelial follower cells, but the effects of t...

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Detalles Bibliográficos
Autores principales: Carey, Shawn P., Martin, Karen E., Reinhart-King, Cynthia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301232/
https://www.ncbi.nlm.nih.gov/pubmed/28186196
http://dx.doi.org/10.1038/srep42088