Stability, structural and functional properties of a monomeric, calcium–loaded adenylate cyclase toxin, CyaA, from Bordetella pertussis

Bordetella pertussis, the causative agent of whooping cough, secretes an adenylate cyclase toxin, CyaA, which invades eukaryotic cells and alters their physiology by cAMP overproduction. Calcium is an essential cofactor of CyaA, as it is the case for most members of the Repeat-in-ToXins (RTX) family...

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Detalles Bibliográficos
Autores principales: Cannella, Sara E., Ntsogo Enguéné, Véronique Yvette, Davi, Marilyne, Malosse, Christian, Sotomayor Pérez, Ana Cristina, Chamot-Rooke, Julia, Vachette, Patrice, Durand, Dominique, Ladant, Daniel, Chenal, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301233/
https://www.ncbi.nlm.nih.gov/pubmed/28186111
http://dx.doi.org/10.1038/srep42065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301233/
https://www.ncbi.nlm.nih.gov/pubmed/28186111
http://dx.doi.org/10.1038/srep42065

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