3-bromopyruvate ameliorate autoimmune arthritis by modulating Th17/Treg cell differentiation and suppressing dendritic cell activation

Recent studies have shown that cellular metabolism plays an important role in regulating immune cell functions. In immune cell differentiation, both interleukin-17-producing T (Th17) cells and dendritic cells (DCs) exhibit increased glycolysis through the upregulation of glycolytic enzymes, such as...

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Detalles Bibliográficos
Autores principales: Okano, Takaichi, Saegusa, Jun, Nishimura, Keisuke, Takahashi, Soshi, Sendo, Sho, Ueda, Yo, Morinobu, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301239/
https://www.ncbi.nlm.nih.gov/pubmed/28186160
http://dx.doi.org/10.1038/srep42412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301239/
https://www.ncbi.nlm.nih.gov/pubmed/28186160
http://dx.doi.org/10.1038/srep42412

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