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Superresolution imaging of nanoscale chromosome contacts

Co-expression of a specific group of genes requires physical associations among these genes, which form functional chromosomal contacts. While DNA fluorescence in situ hybridization (FISH) pinpoints the localization of genes within the 3D nuclear architecture, direct evidence of physical chromosomal...

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Detalles Bibliográficos
Autores principales: Wang, Yejun, Ratna, Prasuna, Shivashankar, G. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301241/
https://www.ncbi.nlm.nih.gov/pubmed/28186153
http://dx.doi.org/10.1038/srep42422